Applied Nursing Research
Volume 18, Issue 1 , Pages 55-58 , February 2005

Lipodystrophy and quality of life in HIV: symptom management issues

  • Patrice K. Nicholas, DNSc, MPH, RN, APRN(BC)

      Affiliations

    • Graduate Program in Nursing, MGH Institute of Health Professions, Boston, MA 02129, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 617 726 1872; fax: +1 617 726 8022.
    • ,
  • Kenn M. Kirksey, PhD, RN, APRN(BC)

      Affiliations

    • Department of Nursing, California State University, Fresno, CA 93740-8031, USA
    • ,
  • Inge B. Corless, PhD, RN, FAAN

      Affiliations

    • Graduate Program in Nursing, MGH Institute of Health Professions, Boston, MA 02129, USA
    • ,
  • Jeanne Kemppainen, PhD, RN

      Affiliations

    • University of North Carolina at Wilmington, School of Nursing, Wilmington, NC 28403-5995, USA

Received 20 March 2004 ,Revised 30 May 2004 ,Accepted 1 September 2004.

References 

  1. Blanch J, Rousaud A, Martinez E, De Lazzari E, Peri JM, Milinkov A, et al. Impact of lipodystrophy on quality of life of HIV-1 infected patients. Journal of Acquired Immune Deficiency Syndromes. 2002;31(4):404–407
  2. Chen D, Misra A, Garg A. Lipodystrophy in human immunodeficiency virus-infected patients. The Journal of Clinical Endocrinology and Metabolism. 2002;87(11):4845–4856
  3. Collins E, Wagner C, Walmsley S. Psychosocial impact of the lipodystrophy syndrome in HIV infection. The AIDS Reader. 2000;10(9):546–550
  4. Duran S, Saves M, Spire B, Cailleton V, Sobel A, Carrieri P, et al. Failure to maintain adherence to highly active antiretroviral therapy: The role of lipodystrophy. AIDS. 2001;15(18):2241–2444
  5. Guaraldi G, Murri R, Orlando G, Orlandi E, Sterrantino G, Borderi M, et al. Morphologic alterations in HIV-infected people with lipodystrophy are associated with good adherence to HAART. HIV Clinical Trials. 2003;4(2):99–106
  6. Heath KV, Chan KJ, Singer J, O'Shaughnessy MV, Montaner JS, Hogg RS. Incidence of morphological and lipid abnormalities: Gender and treatment differentials after initiation of first antiretroviral therapy. International Journal of Epidemiology. 2002;51(5):1016–1020
  7. Heath KV, Hogg RS, Chan KJ, Harris M, Montessori V, O'Shaughnessy MV, et al. Lipodystrophy-associated morphological, cholesterol and triglyceride abnormalities in a population-based HIV/AIDS treatment database. AIDS. 2001;15(2):271–273
  8. Heath KV, Hogg RS, Singer J, Chan KJ, O'Shaughnessy MV, Montaner JSG. Antiretroviral treatment patterns and incident HIV-associated morphologic and lipid abnormalities in a population-based cohort. Journal of Acquired Immune Deficiency Syndromes. 2002;30(4):440–447
  9. Heath K, Singer J, O'Shaughnessy MV, Montaner JSG, Hogg RS. Intentional nonadherence due to adverse symptoms associated with antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes. 2002;31:211–217
  10. Holzemer WL, Corless IB, Nokes KM, Turner JG, Brown MA, Powell-Cope GM, et al. Predictors of self-reported adherence in persons living with HIV disease. AIDS Patient Care. 1999;10(2):18–26
  11. Holzemer WL, Spicer J, Wilson H, Kemppainen J, Coleman C. Validation of the quality of life scale: Living with HIV. The Journal of Advanced Nursing. 1998;28:622–630
  12. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care. 1986;24(1):67–74
  13. Robinson FP. HIV lipodystrophy syndrome: A primer. The Journal of the Association of Nurses in AIDS Care. 2004;15(1):15–29
  14. Schambelan M, Benson CA, Carr A, Currier JS, Dube MP, Gerber JG, et al. Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: Recommendations of an International AIDS Society—USA Panel. Journal of Acquired Immune Deficiency Syndromes. 2002;31:257–275
  15. Smith KY. Selected metabolic and morphologic complications associated with highly active antiretroviral therapy. The Journal of Infectious Diseases. 2002;185(Suppl. 2):S123–S127
  16. Ware JE, Sherbourne CD. The MOS 36-item Short-Form Health Survey (SF-36). Conceptual framework and item selection. Medical Care. 1992;30(6):473–483
  17. Wilson IB, Cleary PD. Linking clinical variables with health-related quality of life: A conceptual model of patient outcomes. Journal of the American Medical Association. 1995;273:59–65
  18. Wilson H, Hutchinson S, Holzemer W. Salvaging quality of life in ethnically diverse patients with advanced HIV/AIDS. Qualitative Health Research. 1997;7:75–97

☆ Supported by the American Nurses Foundation (Dr. Kenn M. Kirksey, Dorothy Cornelius/American Nurses Foundation Research Scholar), the Alpha Eta Chapter of Sigma Theta Tau International Honor Society of Nursing, the College of Health and Human Services at California State University, Fresno, CA, and the MGH Institute of Health Professions at Massachusetts General Hospital, Boston, MA.

PII: S0897-1897(04)00092-8

doi: 10.1016/j.apnr.2004.09.012

Applied Nursing Research
Volume 18, Issue 1 , Pages 55-58 , February 2005

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