Applied Nursing Research
Volume 23, Issue 2 , Pages 116-120, May 2010

An intervention to prevent symptoms associated with hepatitis C: a pilot study

  • Donna M. Zucker, RN, PhD

      Affiliations

    • Corresponding Author InformationTel.: +1 413 545 1343 (Work); fax: +1 413 577 2550.

University of Massachusetts, School of Nursing, Amherst, MA 01003, USA

Received 26 March 2008; received in revised form 8 April 2008; accepted 27 April 2008. published online 16 January 2009.

Abstract 

The objectives of this study were to (a) pilot test instruments measuring fatigue and quality of life (QOL); (b) pilot test an exercise intervention; and (c) estimate the effect size of this intervention relative to completion of combination therapy, fatigue, QOL, and walking distance in 20 patients with chronic hepatitis C about to begin interferon alpha and ribavirin treatment. Alpha reliabilities for both the Schwartz Cancer Fatigue Scale and Hepatitis Quality of Life Questionnaire were moderately high. Power analyses of all outcome measures indicated a small effect size and sample size estimate of 30–40 per group to achieve power of >.80.

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PII: S0897-1897(08)00046-3

doi:10.1016/j.apnr.2008.04.003

Applied Nursing Research
Volume 23, Issue 2 , Pages 116-120, May 2010

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